The American Gestapo blocks a promising cancer treatment (1)...


In “Silent Terror,” I briefly discussed the issue at hand:


“I began work on my first scientific problem at the St.Joseph Hospital Laboratory.# Earlier, researchers at the Laboratory had found that prolonged treatment with thymidine, a naturally occurring compound, caused growth inhibition or regression of certain human tumors implanted in nude mice... Clinical trials were initiated at several institutions. In some cases there was a modest antitumor effect, but many patients were underdosed because the drug was insufficiently concentrated. Stehlin and Giovanella## insisted that a major breakthrough in cancer therapy would be achieved if thymidine could be prepared in a more concentrated form. It was my job to find out how. The problem was solved###, and Stehlin wrote:

“'We have done a tremendous amount of experimental work on Tdr (thymidine) during the past few years. Dr. Lockshin is a hardworking and extremely bright scientist. He is overly modest and conservative in evaluating his own work...

“'We must continue this work because I firmly believe something very good will come of it.'


“Whether or not concentrated thymidine would help cancer patients could only be determined by clinical studies, which Stehlin and Giovanella had promised to pursue. But they refused to continue this work. No cancer patient ever received this preparation.” (“Silent Terror,” p. 23)


Explanation of scientific terms:

“(Deoxy)thymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine... (Deoxy)thymidine is one of the four nucleosides in DNA it is a naturally occurring compound that exists in all living organisms and DNA viruses.” (Thymidine, Wikipedia)

“A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts...” (Nude mouse, Wikipedia)


Metastatic melanoma – a terrible disease...


The clinical trials that were held before my arrival in Houston were on melanoma patients. Disseminated (Stage IV, metastatic) melanoma was – and remains to this day - a particularly intractable and often rapidly proliferating tumor:


“Melanoma is the most dangerous type of skin cancer. Globally, in 2012, it newly occurred in 232,000 people. In 2015 there were 3.1 million with active disease which resulted in 59,800 deaths.


“Melanomas are usually caused by DNA damage resulting from exposure to ultraviolet light from the sun. Genetics also plays a role.


“Various chemotherapy agents, including temozolomide, dacarbazine (also termed DTIC), immunotherapy (with interleukin-2 (IL-2) or interferon (IFN)), as well as local perfusion, are used by different centers. The overall success in metastatic melanoma is quite limited.


“When there is distant metastasis, the cancer is generally considered incurable. The five-year survival rate is less than 10%. The median survival is 6–12 months. Treatment is palliative, focusing on life extension and quality of life.” (Melanoma, Wikipedia)


“The risk of melanoma increases as people age. The average age of people when it is diagnosed is 63. But melanoma is not uncommon even among those younger than 30. In fact, it’s one of the most common cancers in young adults (especially young women).” (Key Statistics for Melanoma Skin Cancer, The American Cancer Society, 2018)


“Because stage IV melanoma is hard to cure with current treatments, patients may want to think about taking part in a clinical trial...” (The American Cancer Society, 2018)

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One would like to think that treament of such a terrible disease would be a humanitarian, medical concern. But the secret political police of police-state dictatorship USA had and have a different point of view.


The depravity of fascist CIA/FBI etc. murderers lacking any human feeling whatsoever.


To be continued...

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# The Stehlin Foundation was associated with St. Joseph's Hospital.

## See previous post.

### Antitumor activity and minimal toxicity of concentrated thymidine infused in nude mice
(Cancer Research 45, 1797-1802 · (1985), A, Lockshin et al.)


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Перед нами сейчас - коварный и опасный мошенник, расист, лжец и фашист Дональд Трамп, порочный Конгресс, нацистские ФБР - ЦРУ, кровавые милитаристы США и НАТО >>> а также и лживые, вредоносные американские СМ»И».


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Правительство США жестоко нарушало мои права человека при проведении кампании террора, которая заставила меня покинуть свою родину и получить политическое убежище в СССР. См. книгу «Безмолвный террор — История политических гонений на семью в США» - "Silent Terror: One family's history of political persecution in the United States» - arnoldlockshin.wordpress.com

Правительство США еще нарушает мои права, в течении 14 лет отказывается от выплаты причитающейся мне пенсии по старости. Властители США воруют пенсию!!

ФСБ - Федеральная служба «безопасности» России - вслед за позорным, предавшим страну предшественником КГБ, мерзко выполняет приказы секретного, кровавого хозяина (boss) - американского ЦРУ (CIA). Среди таких «задач» - мне запретить выступать в СМИ и не пропускать большинства отправленных мне комментариев. А это далеко не всё...

Арнольд Локшин, политэмигрант из США


BANNED – ЗАПРЕЩЕН!!

ЦРУ - ФСБ забанили все мои посты и комментарии в Вконтакте!
… и в Макспарке!